'I lost 5 stone on Mounjaro but made stark discovery the moment I stopped it'

Weight loss injections with everyone from to Sharon Osbourne

Known as GLP-1 agonists, Mounjaro, Wegovy and Ozempic slow digestion and reduce appetite by mimicking hormones which regulate hunger and feelings of fullness. They are designed to act like one of these hormones, known as glucagon-like peptide 1 (GLP-1).

Experts were amazed when Mounjaro, also known by its proper name tirzepatide, helped users in trials and outperformed previous jabs. Now ever more powerful versions of these drugs are in the research pipeline.

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However, one TikTok user used her platform to share her experience on Mounjaro, and explained one huge problem she had encountered taking the jabs. Mary, known as @Contrary_mary1 on the social media platform, said: "I seem to have landed on the Mounjaro side of TikTok recently so I thought I'd just put my little take on it.

"I started taking Mounjaro in July 2024. Start of the summer holidays. My starting weight was 17 and a half stone and I had a goal to lose six stone, to get to 11 and a half stone.

"So I started taking it and it worked brilliantly for me. I lost five stone between the end of July and the end of December, taking me down to 12 and a half stone, which is where I stopped it. Not because I wanted to - I absolutely loved it - but because I couldn't afford it anymore. So I stopped taking it and I went cold turkey - just literally used my last pen and then went off it."

It was all downhill for the mum of three, who admitted that she quickly fell back into her old habits. "Naively, I assumed the good habits that I'd got into over that over the five, six months I was taking it would just stick with me. That didn't happen," she confessed. "I would say almost immediately, all of the food noise came back. All of the cravings came back. My willpower? Completely non-existent.

"What that's meant is in the four months I've been off it, I've regained a stone, so current weight is 13 and a half stone. Two stone to go until my goal weight."

Mary went on to advise her followers to "have a plan" if thinking about stopping the weight loss injections. "That is just my honest review. So for anybody that's currently taking Mounjaro and is thinking about coming off, these will be my suggestions. Feel free to ignore them because obviously I'm not doing a very good job.

"Have a plan in place. If you, like me, when you've taken Mounjaro, haven't even needed to use your will power, you haven't even needed to count calories, it's just been a walk in the park, don't expect that to continue after you stop taking it because for me it didn't.

"So have a plan in place - whether that's counting calories or intermittent fasting, whether that's reducing your portion sizes, plan for it in advance."

And it looks as though Mary isn't the only one who gained weight back after coming off the drug, as many took to the comments to share similar stories. One person said: "I’m 3 weeks off of it & nearly a STONE up. I’m still running, weightlifting and calorie counting I’m spiralling…."

"I lost weight. I stopped it and regained it all back," another penned.

Someone else said: "I've been off 2 weeks because I cant find a pharmacy that will prescribe it at my weight and all the food noise is back, cravings etc."

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