Alzheimer's double attack on the brain: slow death in the first stage, rapid destruction in the second!

Alzheimer's disease can damage the brain in two stages. This research is supported by the National Institutes of Health (NIH) and uses cutting-edge brain mapping techniques.

Alzheimer's disease is a progressive neurodegenerative disease that affects memory, thinking and behavior. Now, a new study has uncovered how the disease damages the brain in two stages. According to new research, Alzheimer's disease may damage the brain in two stages. The research is supported by the National Institutes of Health (NIH) and used cutting-edge brain mapping techniques.

The researchers explained that the first stage begins slowly and silently, when a person does not have memory problems. It affects only a few vulnerable cells. In contrast, the second stage causes more extensive damage and is accompanied by the rapid growth of common symptoms of Alzheimer's, such as plaques and tangles.

What does the expert say?

Dr. Richard J. Hodes, director of the NIH's National Institute on Aging, said that a challenging aspect of Alzheimer's is that most brain damage occurs when symptoms have not yet appeared. The results of this research can help us understand for the first time what is happening in the brain in the early stages of the disease.

Study done on 84 people

In this research, the brains of 84 people were analyzed and its result has been published in Nature Neuroscience. Research has shown that a specific type of cell (called inhibitory neuron) is most affected in the first stage of Alzheimer's disease. Apart from this, the research has confirmed the already known facts about the damage caused to the brain by Alzheimer's and has discovered new changes.

The researchers studied the middle temporal gyrus, a part of the brain that controls language, memory and vision. They found that the effects of Alzheimer's disease start slowly at first, including changes such as activation of the brain's immune system and death of neuronal cells. However, the study found that the second stage, in which memory problems and other symptoms appear, affects the brain more rapidly.

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